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  #51 (permalink)  
Old 07-07-2009, 02:08 PM
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Kraig Biocraft Laboratories, Inc. (KBLB.OB) Utilizing Latest Genetic Technology in Search of Super-Fiber

Kraig Biocraft Laboratories Inc. is a company focused on the development of high performance technical fibers and polymers utilizing spider genes for insertion into silkworms. The idea is to create a transgenic variety of silkworms capable of spinning a new “super fiber” that is similar or an exact copy of natural spider silk, which is one of the strongest and most resilient fibers known.

Kraig Biocraft has acquired the exclusive rights, in their field of use, to the genetic sequences patented by the University of Wyoming and the genetic engineering technology developed by the University of Notre Dame. The company is also working in conjunction with leading genetic engineers at these universities toward the goal of producing a transgenic variety of silkworms.

While the production of a “super fiber” is the primary focus of Kraig Biocraft at this time, the company is also considering the production of other unique proteins utilizing transgenic silkworms as a unique protein expression platform. There is thought to be a large, viable market for these unique proteins within the pharmaceutical, biotechnology and other research driven industries.

As part of the company’s intellectual property portfolio, Kraig Biocraft has the exclusive rights to use the patented spider silk gene sequences in silkworms within the United States. The company’s intellectual property portfolio also includes a separate US provisional patent application regarding certain methodologies, genetic sequences, organic polymers and composites of fibers. It is expected that Kraig Biocraft’s intellectual property portfolio will continue to grow over the coming years.
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  #52 (permalink)  
Old 07-09-2009, 12:16 PM
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Kraig Biocraft Laboratories, Inc. (KBLB.OB) Aiming for Multi-Million Dollar Fiber

Kraig Biocraft Laboratories Inc. is a biotechnology company pursuing a unique protein expression system with the goal of producing a new generation of technical fibers. The company is making use of state of the art genetic techniques in order to develop a transgenic silkworm capable of producing spider silk.

Specifically, the company is aiming towards a sub-sector of the “technical textiles” market known as the high-performance fibers market. All of the products in this area are significantly stronger than steel of the same weights and diameters. Due to this superior strength and toughness, these fibers have been widely adopted into a variety of industrial applications.

The high-performance fibers market can be broken down into two main areas. The first of these areas is aramid fibers. The best known of these fibers is DuPont’s Kevlar, which holds a significant share of this market and produces over $5 billion in sales for DuPont. Kevlar’s very high strength and lightweight qualities have allowed it to dominate this market for over four decades.

The second classification of high-performance fibers is ultra-high molecular weight polyethylene fibers. An example of this type of product is Spectra, which is produced by Honeywell. Spectra has applications for use in bullet resistant vests, helmets, armored vehicles, and marine-related applications.

Another example is Dyneema, which is produced by Dutch firm DSM NV. Dyneema is an important component in ropes, cables and nets used in fishing, shipping and offshore industries due to its ultra-high strength, resistance to moisture and ability to float in water.

The worldwide market for these types of fibers is estimated to be about $90 billion. This market has grown rapidly over the past 10 years and is expected to sustain a rapid growth rate going forward. Despite the formidable competition, Kraig Biocraft is expected to carve out a profitable niche in the market with spider silk products.

Spider silk has some distinct advantages over synthetically derived products. For example, spider silk is unmatched by any man-made or natural product when it comes to its ability to absorb energy prior to fiber breakage. And obviously, spider silk is a natural product, not made with toxic chemicals, and it is biodegradable. If Kraig Biocraft is successful, they will have a unique product worth at least several hundred million dollars.
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  #53 (permalink)  
Old 07-14-2009, 04:08 PM
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Kraig Biocraft Laboratories Inc. (KBLB.OB) and Team of Scientists Successfully Create 8 Spider Silk-Based DNA Constructs

Kraig Biocraft Laboratories Inc. develops protein-based fiber using recombinant DNA technology. The company focuses on spider silk because of its exceptional strength and durability. Some spiders produce up to seven different types of silk, depending on its use, for catching prey, spinning a web, or traveling.

Since spiders are cannibals and hard to keep in colonies, the company maintains its focus on reproducing the fibers using transgenic silkworms. The idea is to create a transgenic variety of silkworms capable of spinning a new “super fiber” that is similar or an exact copy of natural spider silk, which is can be used in military and police departments, industrial and consumer applications, as well as for the aero-space industry.

In May of this year, Kraig Biocraft announced that it has successfully created eight DNA constructs, with the help of a team of scientists. Having teamed up with the University of Notre Dame to move into the $92 billion market for technical fibers, the news is a milestone for the company and the university.

“These constructs include a number of new DNA combinations that are truly exciting,” said CEO Kim K. Thompson. “The increases in laboratory productivity over the last eight months are now enabling us to do more and to do it faster. This number of unique genetic constructs is a new breakthrough for the company. Each of these constructs has the potential to result in the development of a new polymer or high performance fiber.”

In layman’s terms, the genetic constructs are packets of DNA that act as a blueprint for the creation of new polymers and spider silk-based proteins. According to the company and participating scientists, the experiments have increased dramatically.
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  #54 (permalink)  
Old 07-20-2009, 02:11 PM
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Kraig Biocraft Laboratories, Inc. (KBLB.OB) Establishes Value Beyond Spider Silk

Kraig Biocraft Laboratories, Inc., the biotech company currently using genetic modification of silkworms in an effort to produce spider silk, is playing a leading edge role in one of today’s major scientific endeavors. The use of genetic engineering to modify life forms for the production of unique proteins promises to change the world of materials and research, allowing us to effectively customize what we work with. Though Kraig Biocraft has gained much exposure for its progress in the pursuit of spider silk, it is increasingly being recognized for its developments in the implementation of genetic engineering.

Proteins are a key element of living things, and can come in an almost endless variety, each having a unique set of properties that can be used in research, pharmaceuticals, and materials. But specific proteins can be very difficult to come by, especially in the volumes required for different applications. Proteins are produced by genes, which provide the coded recipes for the various proteins. Most of the proteins scientists want occur in nature, but seldom in the quantities needed. Genetic engineering can help solve the supply problem.

By isolating and analyzing the genes that produce the desired proteins, scientists can identify the specific chemical formula of the genes, called gene sequencing, allowing them to replicate the genes. Knowing how to replicate a gene means you are no longer dependent upon nature as its source. However, in order to actually make and operate a functional gene, you still need a host organism. Bacteria are frequently used as genetic host organisms. Re-created genetic material from the original organism is introduced into the host organism, using advanced genetic engineering techniques, allowing the host organism to now produce the corresponding proteins, called protein expression.

It’s not an easy process. First of all, scientists don’t yet know all of the genetic codes available in nature. And, once known, it can be difficult to find an appropriate host and develop the sophisticated techniques required to introduce the genetic material into the host. Kraig Biocraft Laboratories is one of the companies in the forefront of this field. Utilizing the silkworm as the genetic host, and introducing isolated spider genes, the company is closing in on the economically viable production of spider silk, something that has never before been accomplished.
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  #55 (permalink)  
Old 07-20-2009, 02:34 PM
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Kraig Biocraft Laboratories, Inc. (KBLB.OB) Assembles Strong Advisory Board

Kraig Biocraft Laboratories, Inc., the biotech company known for its pioneering work in genetic engineering for the production of spider silk and other polymers, is constantly breaking new ground in the field of genetics. As such, it is not surprising that they have assembled a remarkable team of scientific advisors to play a major role in everything they do.

• Malcolm J. Fraser, Jr., Ph.D, specializes in molecular genetics, and currently heads the Fraser Laboratory at the University of Notre Dame. During his post-doctoral work at Texas A&M, Dr. Fraser was part of the team which developed the genetic expression system for producing organic molecules, including pharmaceuticals, on an industrial scale. He is the co-inventor of the “piggyBac” gene splicing technology, and the named inventor for various patents involving its improvement.

He was recently selected as a fellow of the American Association for the Advancement of Science, in recognition for his distinguished contributions to genetics and transgenesis, as well as for his discovery of the piggyBacs transposable element and derived transgenic vector system.

Dr. Fraser was also awarded $2.5 million from the Bill and Melinda Gates Foundation to fund “deliverable technologies” in the field of transgenesis for the prevention of mosquito born disease.

• Randy Lewis, Ph.D., is internationally renowned for his work on spider silk, and is the named inventor for a number of patents relating to spider silk polymers. He currently heads the Lewis Laboratory at the Department of Molecular Biology at the University of Wyoming, where he focuses on the underlying genetics of spider silk polymers.

• Donald L. Jarvis, Ph.D., is an expert on biosynthesis, and its practical genetic engineering applications. He has many patent applications and intellectual property licensing agreements involving biosynthesis technologies with potential applications for pharmaceutical production. He currently heads a research laboratory in the Department of Molecular Biology at the University of Wyoming.

The strength of this advisory board is one of the reasons Kraig Biocraft has gained recognition for its work in genetic engineering, over and above its ongoing pursuit to produce commercially viable spider silk.
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  #56 (permalink)  
Old 07-21-2009, 02:18 PM
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Kraig Biocraft Laboratories, Inc. (KBLB.OB) Assembles Strong Advisory Board

Kraig Biocraft Laboratories, Inc., the biotech company known for its pioneering work in genetic engineering for the production of spider silk and other polymers, is constantly breaking new ground in the field of genetics. As such, it is not surprising that they have assembled a remarkable team of scientific advisors to play a major role in everything they do.

• Malcolm J. Fraser, Jr., Ph.D, specializes in molecular genetics, and currently heads the Fraser Laboratory at the University of Notre Dame. During his post-doctoral work at Texas A&M, Dr. Fraser was part of the team which developed the genetic expression system for producing organic molecules, including pharmaceuticals, on an industrial scale. He is the co-inventor of the “piggyBac” gene splicing technology, and the named inventor for various patents involving its improvement.

He was recently selected as a fellow of the American Association for the Advancement of Science, in recognition for his distinguished contributions to genetics and transgenesis, as well as for his discovery of the piggyBacs transposable element and derived transgenic vector system.

Dr. Fraser was also awarded $2.5 million from the Bill and Melinda Gates Foundation to fund “deliverable technologies” in the field of transgenesis for the prevention of mosquito born disease.

• Randy Lewis, Ph.D., is internationally renowned for his work on spider silk, and is the named inventor for a number of patents relating to spider silk polymers. He currently heads the Lewis Laboratory at the Department of Molecular Biology at the University of Wyoming, where he focuses on the underlying genetics of spider silk polymers.

• Donald L. Jarvis, Ph.D., is an expert on biosynthesis, and its practical genetic engineering applications. He has many patent applications and intellectual property licensing agreements involving biosynthesis technologies with potential applications for pharmaceutical production. He currently heads a research laboratory in the Department of Molecular Biology at the University of Wyoming.

The strength of this advisory board is one of the reasons Kraig Biocraft has gained recognition for its work in genetic engineering, over and above its ongoing pursuit to produce commercially viable spider silk
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  #57 (permalink)  
Old 07-22-2009, 03:30 PM
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Kraig Biocraft Laboratories, Inc. (KBLB.OB) Leveraging Their Research into Spider Silk

Kraig Biocraft Laboratories Inc. is a biotechnology development company focused on genetically engineered high performance polymers and technical fibers. The company is currently working on research to genetically coax silkworms into producing spider silk.

Kraig Biocraft believes that spider silk is a “super fiber” that will have numerous commercial and consumer applications. The overall marketplace for these types of fibers in general is approximated to be $90 billion. According to Emerging Growth Research, an independent industry research firm, if Kraig Biocraft is successful is achieving its goal and producing a spider silk fiber product, “the technology will likely immediately be worth at least several hundred million dollars.”

In order to reach its goal, Kraig Biocraft has leveraged its efforts by working cooperatively with select university laboratories. This arrangement allows the company to bring technologies from diverse research institutions and combine them.

As part of this strategy, Kraig Biocraft licenses university intellectual properties in genetics and genetic engineering, thus allowing them to tap some of the greatest minds in the field. To date, the company has licensed technology from the University of Wyoming and the University of Notre Dame.

The genetic technology involved is very complex. In order to have silkworms produce spider silk, scientists had to develop the technology to successfully insert into silkworms the DNA packets containing the unique gene sequence used by spiders to produce silk.

Since the company first obtained the right to use the spider silk gene sequence from the University of Wyoming, Kraig Biocraft has surprised many with the speed of the advances they’ve made. Kraig Biocraft now performs thousands of ‘insertions’ in a single week. This work is occurring at the company’s research program at the University of Notre Dame where substantial progress is being made in the successful insertion of DNA packets, both with the number and proportion of insertions.

As Kraig Biocraft’s success with insertions increases, so does the company’s chance of developing a viable multi-million dollar product.
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  #58 (permalink)  
Old 07-27-2009, 01:58 PM
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Kraig Biocraft Laboratories, Inc. (KBLB.OB) Part of Hot Venture Industry

Kraig Biocraft Laboratories, Inc., the Michigan-based research group best known for its innovative research in genetic engineering for the production of spider silk, is representative of what some are saying will be the 21st century’s most important scientific and industrial movement, biotechnology. Reflecting this is the fact that biotechnology, loosely defined as the application of advanced microbiological sciences for industrial or health objectives, is still the darling of venture capitalists.

According to a Reuters article by David Lawsky, “Biotechnology leapt ahead as the biggest recipient of U.S. venture capital money in the second quarter”, indicating that “the venture capital industry put $3.67 billion into 612 separate companies or deals during the second quarter, of which $1.5 billion involved first time funding”, though the article went on to say that funding was still well below levels earlier in the decade.

The article quoted Tracy Lefteroff, the head of PricewaterhouseCoopers venture capital practice, as saying that the reason for the growth in biotechnology funding was obvious — there are more acquisitions and initial public offerings in life sciences. “Life sciences is one of the few sectors that has a regular stream of exit events,” Tracy Lefteroff said in a conference call. “If you’re an investor in a venture fund you’re going to put your money where you believe you have the best chance to get liquidity. At this point, life science is looking to be fairly attractive compared to the other areas.”

Kraig Biocraft is unique in biotechnology, in that it is using genetic engineering to produce commercially viable spider silk, something that has never been done before. Their groundbreaking work involves the insertion into silkworms of DNA packets containing the unique gene sequence used by spiders to produce silk. Since Kraig Biocraft first obtained the right to use the spider silk gene sequence in this particular field of research, they have made remarkable progress with the insertion process.
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  #59 (permalink)  
Old 08-03-2009, 10:44 AM
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Kraig Biocraft Laboratories, Inc. (KBLB.OB) Aims to Turn Spider Silk into a Commercially Available ‘Super Fiber’

Kraig Biocraft Laboratories Inc. is a biotechnology company using state-of-the-art genetic techniques to develop transgenic silkworms capable of producing spider silk. The company believes that because of spider silk’s characteristics, it has the potential to become a ’super-fiber’ with many commercial applications.

Spider silk is among the strongest fibers produced in nature. The silk has several properties that are unmatched by man-made fibers. One property is spider silk’s capacity to absorb energy and to dissipate this energy in a controlled manner. This property makes spider silk especially attractive for applications where energy absorption is a key design factor such as bulletproof vests, suspension cables, parachute cords, artificial ligaments, etc.

Another significant property of spider silk is its extreme resistance to breaking under strain. In this respect, spider silk significantly outperforms virtually all known natural and man-made fibers. It is this property that makes spider silk appealing for use as a ’super fiber’.

With spider silk products, Kraig Biocraft will be attempting to break into the market for high performance technical fibers. This market generates $90 billion per year, with the United States accounting for more than half of the market. The industry has experienced significant growth over the past 10 years and growth in the sector is expected to continue.

There are well-established products in the marketplace – Kevlar, Spectra, Dyneema – which will provide competition for the company’s products. However, there are certain properties that are inherent to spider silk, such as the ability to absorb energy, making it superior to these synthetic products.

Spider silk, being all natural, should also give Kraig Biocraft an advantage over competitors’ products which are made in a manufacturing process using toxic chemicals and are highly pollutive to the environment. Based on these factors, the company should be able to find a profitable niche for their products in the marketplace.
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  #60 (permalink)  
Old 08-03-2009, 10:48 AM
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eDOORWAYS Corp. (EDWY.PK) on Target for Soft Launch Date; Provides Final Update on Pre-Launch Demonstration

eDOORWAYS Corporation Friday provided the investment community with a final update on its proposed walk-through presentation described in the press release issued on Friday, July 24, 2009.

“Recently, we extended an offer to show SOLVE to those shareholders who would like to gain a better understanding of the design and workings of the SOLVE doorway via a live walk-through demonstration,” stated eDOORWAYS Chairman and CEO Gary Kimmons. “These same shareholders would then have the duty of giving an unbiased reporting to those shareholders who were not made privy to the demonstration.

“Our offer was made with the provision that any shareholder desiring to view the presentation would be required to make necessary representation that they were, in fact, a shareholder of record and that they would comply with certain SEC legislation that would limit their activity in the marketplace as it relates to trading eDOORWAYS securities. This placed a burden on most of our shareholders that has proven difficult to overcome.

“Of the more than two thousand shareholders of record holding eDOORWAYS stock today, virtually no one elected to participate. There were fewer than five verified shareholders of record who chose to do so. This number represents less than 1% of the current shareholders holding eDOORWAYS stock of which collectively hold less than 1% of the Issued and Outstanding Shares. Unfortunately, these numbers would have had to be much greater for us to justify going forward with the demonstration.

“First, the cost of doing so would have been prohibitive to accommodate such a small number of volunteers. Even more important for us all to consider, however, is the relative risk of entrusting an extremely limited number of participants, whom combined hold a fraction of the overall share count, with the responsibility of reporting their observations and opinions to our entire shareholder base and the rest of the world. A fair representation of shareholder interest for an example would have been a greater number of shareholders (twenty or thirty) irrespective of stock ownership, or, a fewer number of shareholders with significant (thirty to sixty million shares) combined holdings.

“We do not believe that it is fair to you, our shareholders, to risk the value of your holdings on the basis of one or two opinions from individuals who combined may have much less at stake than you. The question we had to ask ourselves was this: ‘Is this group truly capable of portraying SOLVE as it should be seen and will this group be considerate of shareholder risk?’

“With the soft launch now looming as a near-term event, we believe it to be far better for us to wait until everyone can see the platform. We ask for your patience as we await this event, and we thank you for being loyal and supportive investors in eDOORWAYS Corporation.”

eDOORWAYS’ executive management reaffirmed that the company is still on track for a timely soft launch on October, 1, 2009. In the press release, the company also said that auditors will begin their review for the filing of Form 10K sometime in the next seven business days, which should keep eDOORWAYS on course for its target date for filing the 10K along with first and second quarter statements.
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