KBLB Kraig Biocraft Laboratories Inc. - KBLB - Page 2

QualityStocks · #11 (**permalink**) 02-17-2009, 01:19 PM

Kraig Biocraft Laboratories, Inc. (KBLB.OB) is Led By a Group of Visionary Researchers

Kraig Biocraft Labs, a biotech research firm with its sights set on producing spider silk in commercial quantities, is ever-advancing toward its goal with the help of an extremely talented group of scientists. With the success of their endeavors rapidly materializing as an eventuality, as opposed to a possibility, the Kraig Labs researchers are nearing the culmination of more than 30 years of combined experience with complex protein polymers derived from the silk of a spider.

The lineup begins with Dr. Malcolm Fraser, graduate of Ohio State University, whose work in developing a genetic expression system now plays an instrumental role in the industrial production of organic molecules. Dr. Fraser is also the co-inventor of the “piggyBac” gene-splicing method, an achievement which led to his being named a fellow of the American Association for the Advancement of Science.

Aiding Dr. Fraser is Dr. Randy Lewis, a biochemist with accreditation from UC San Diego, and holder of numerous patents relating to the field of spider silk polymer production. Dr. Lewis has, quite impressively, been dedicated to the pursuit of spider silk research since 1990, when he contributed to the first of more than a dozen scientific papers on the subject.

Rounding out the group is Dr. Donald Jarvis, who obtained his Ph.D in Virology at Baylor College of Medicine. Like Dr. Fraser, Dr. Jarvis holds several patents in the field of molecular biology, and genetic engineering. Though his work with spider silk did not begin until after 2000, Dr. Jarvis has been a leading authority in biochemistry for more than 20 years.

These individuals, along with others, are working tirelessly to effect the development of a method by which spider silk may be commercially produced. The technical possibilities with respect to hypothetical uses of the substance following their success are nearly limitless. Kraig Biocraft Laboratories is approaching this goal by leaps and bounds, thanks to the vision and ingenuity of these talented scientists.

QualityStocks · #12 (**permalink**) 02-17-2009, 01:22 PM

Kraig Biocraft Laboratories, Inc. (KBLB.OB) to Discuss Proposed Forward Stock Split

Today, Kraig Biocraft Laboratories announced that its Board of Directors will be contemplating a proposed forward stock split of the company’s common stock. The meeting has been scheduled to take place after the close of the markets on Wednesday, February 18.

Kraig Biocraft Laboratories, Inc. (KBLB), a biotechnology company, has their focus on developing high performance polymers and technical fibers. The company is utilizing their proprietary genetic engineering technology to develop and produce polymers and protein-based materials, including Spider silk, which may have numerous commercial and consumer applications.

QualityStocks · #13 (**permalink**) 02-18-2009, 04:28 PM

Kraig Biocraft Laboratories, Inc. (KBLB.OB) Buyout Potential

It is no mystery that Kraig Biocraft Laboratories is a research and development company. They do not have the infrastructure to immediately compete against the biggest players in the technical textiles market. They do not need to focus on supply chain management or building a large sales and marketing team. This is simply not their goal.

Investors or potential investors should not be alarmed by this “lack of infrastructure” if you will. The long-term performance of one’s investment in this company is based on its response to two fundamental questions: 1) Can Kraig Biocraft harness its spider silk technology into a package that can be readily used in commercial applications, and 2) Does Kraig Biocraft have the intellectual property rights behind its technology?

From recent statements delivered within the past year from CEO Kim Thompson, it appears that Kraig is very much on the verge of fulfilling both of the questions above. Once they are met, Kraig will be seen as an attractive buyout to those companies having the established infrastructures capable of delivering Kraig’s technologies in commercial applications. DuPont and Honeywell would be the first two major players that come to mind.

Amid the economic downturn, the number of mergers and acquisitions within the biotech fields has remained consistent and extremely beneficial to the company taken over. Look at other buyout offers within the biotech field during the past two years:

• At $1.72 per share, synthetic fuels and fertilizer technology company Rentech Inc was proposed to be bought out at $2.70 per share by Sherwood Investments Overseas Ltd (November 2007) - Rentech shares rose more than 32 percent on the news that day
• When GlaxoSmithKline PLC proposed to buy Genelabs Technologies Inc. for $1.30 per share, the stock price of Genelabs rose 430% (October 2008)

Overall, it appears that Kraig’s stock price may move moderately from here on findings in the laboratory or based on the progress with current or new patent filings. The huge jump will take place when a takeover is announced. Whether this news takes place in a year or in two years, the investment will be well worth the wait considering the potential gains that can be made in that one day.

QualityStocks · #14 (**permalink**) 02-20-2009, 06:41 PM

Review of Kraig Biocraft Laboratories, Inc. (KBLB.OB) Recent Progress in the Labs

In the past four weeks, Kraig Biocraft Laboratories has had two significant announcements. Exactly a month ago, the company announced that its scientific team succeeded in activating fluorescent marker gene sequences which the researchers incorporated into spider silk DNA packets. This means that the DNA insertion packets are working and that Kraig Biocraft has succeeded in obtaining chromosomal insertion and expression.

CEO Kim K. Thompson had this to say after the success, “Not only are the DNA packets incorporating themselves into the silkworm chromosome as expected, the silkworms are actually producing the fluorescent proteins as they are instructed to do by the genetic coding in the spider silk insertion packets… This is a dramatic shift forward in the Company’s spider silk and high performance polymer development program.”

In more recent news, the company announced that it has accomplished five thousand genetic transfers in a single week using the newly designed DNA insertion packets. The achievement exceeded the company’s wildest expectations in 2008, and more importantly, the research team is now performing these gene transfers in large numbers on a regular basis. With this number of gene insertions, the odds of the company developing a viable polymer is increasing exponentially.

QualityStocks · #15 (**permalink**) 02-24-2009, 01:15 PM

Kraig Biocraft Laboratories, Inc. (KBLB.OB) is on the Cusp of Unlocking Exciting Technology

We have been covering Kraig Biocraft Laboratories since December of last year. Those who have read our articles understand why we are excited about this company’s prospects to develop a “super fiber” that can be sold into the technical textiles industry. This super fiber, spider silk, has truly remarkable properties and may have numerous commercial and consumer applications.

Currently Kraig Biocraft is in the research and development stage, but has been making excellent progress in the labs and is now capable of accomplishing five thousand genetic transfers in a single week using its newly designed DNA insertion packets. Additional lab personnel and a change in techniques has significantly boosted productivity and the company’s odds of success.

Artificial or transgenic production of spider silk will surely be viewed by the scientific community as a major breakthrough. Such a development would also likely yield significant coverage in the general business and popular press sectors, perhaps offering Kraig Biocraft Laboratories significant public relations exposure, which could easily drive its market value to much higher levels.

We are very pleased that Kraig Biocraft aligned itself with Dr. Malcolm Fraser, who was the inventor of the piggyBac technique for gene transposition, and Dr. Randy Lewis, who is one of the world’s cheif authorities on spider silk. As a meaningful shareholder in the company, Dr. Fraser stands to gain substantial monetary rewards, in addition to significant academic and scientific accolades.

If/once Kraig Biocraft achieves a major breakthrough in the laboratory, it could take awhile to completely refine the process. It is anticipated that the company’s management team would actively pursue licensing agreements or the outright sale of the company during this time. Should the company achieve its desired transgenic goals, we believe it would be unlikely that the company would actually produce the fibers on its own as this would require very specialized management skills and extensive amounts of fresh capital. An acquisition would be much more likely.

QualityStocks · #16 (**permalink**) 02-27-2009, 05:08 PM

Kraig Biocraft Laboratories Inc. (KBLB.OB) has No Need for FDA Approval

One of the most significant hurdles most biotechnology companies have to overcome is FDA approval. To receive FDA approval, a process that can take up to two and a half years, the company must submit an application (usually about 100,000 pages) to the FDA. This extensive process has been a barrier to many new products that will never compete in the market.

Fortunately for Kraig Biocraft, their technology doesn’t have to be approved by the FDA, which makes it much easier for investors to monetize their investment since the costs are significantly reduced and the time to market is much shorter. The potential for success is also much greater as only 5 out of 5,000 compounds discovered in the pre-clinical stage ever make it through the entire FDA approval process.

QualityStocks · #17 (**permalink**) 03-04-2009, 11:07 AM

Kraig Biocraft Laboratories, Inc. (KBLB.OB) is Poised for Success

When some people measure the value of a company, the primary aspect they concern themselves with, is dollars and cents – i.e. the bottom line. This method of evaluation would be fine if life was strictly a numbers-game, but it is not. This narrow view eludes the true spirit of industry, which is the betterment of all mankind.

Few companies can claim to have changed the world through innovation, but if Kraig Labs continues its current rate of progression, it is a claim that will not be unfounded for them. Scientists have tried for decades to exploit the unequaled uniqueness of spider silk, but to no avail. Only Kraig Labs has utilized DNA transfers to effect the production of spider silk by silkworms through a sort of ‘genetic surrogacy’, which allows the circumvention of the fact that spiders cannot be raised in colonies due to a natural tendency toward cannibalism. This innovative approach has likely put this company closer to commercial production of the substance than anyone ever before.

When it comes to high-potential, ground-floor opportunities, Kraig Biocraft Laboratories is unsurpassed by the majority. They are teetering on the brink of a breakthrough that will forever alter the landscape in the field of engineering.

QualityStocks · #18 (**permalink**) 03-04-2009, 11:09 AM

Spider On Your Back

Is that shirt on your back made partially out of spider silk? Well, not yet. But that question may have a different answer in the not too distant future. Researchers around the world are working hard to untangle one of nature’s greatest mysteries: exactly how do spiders make silk and can it be produced on a commercial scale by man.

The reason for all the interest in spider silk relates to its extraordinary qualities, unlike anything currently available. Although there are different types of spider silk, and different ways of measuring strength, it is generally considered to have a tensile strength (ability to resist tearing) far greater than steel by weight, in addition to being much more elastic than other tough fibers, such as Dupont’s Kevlar®, Honeywell International Inc.’s (NYSE: HON) Dyneema, or Cytec Industries, Inc. (NYSE: CYT) and Hexcel Corp.’s (NYSE: HXL) carbon fibers. It is also hypoallergenic and biodegradable. But perhaps the most remarkable property of spider silk is its weight, or lack of it. All of its unique features are wrapped up in a molecular structure so light that a strand of spider silk long enough to circle the earth could weigh less than one pound.

Strength and elasticity, without significant weight, is a combination of properties offering countless industrial and commercial applications. But it does nobody any good if it can’t be produced in the volumes necessary, and therein rests the biggest problem. There is currently no proven large scale way to produce spider silk. It turns out that you can’t just corral a bunch of spiders to spin their magic. Spiders are, by nature, predatory, and will attack one another. So the search is on for a way to transplant the already identified genetic machinery of the spider into more production friendly animals.

Researchers in various universities have uncovered the structure of different spider silks, and have developed some laboratory level procedures for producing it, but few individual companies have taken on the challenge.

• EI DuPont de Nemours & Co. (NYSE: DD) took an early look at spider silk, creating fibers that had two of the main proteins, but their recent progress is unclear, and they still depend upon their Kevlar® aramid fiber for the marketplace.
• Researchers at the University of Wyoming, University of the Pacific, the University of California, and at Shinshu University in Japan uncovered the molecular structure of the gene for the protein that various female spider species use to make their silken egg cases, but not how to produce the silk in large amounts.
• Nexia Biotechnologies in Canada has managed to produce the spider silk protein in the milk of transgenic goats, but ongoing technical issues related to commercial scale production has led them to refocus on small scale fiber applications.

But now another company, Michigan-based Kraig Biocraft Laboratories, Inc. (OTCBB: KBLB), has taken a unique approach. The development stage biotechnology company has successfully inserted spider silk DNA packets into silkworms, allowing the silkworms to produce spider silk related proteins. And recently the company announced that it has performed 5,000 such insertions in a single week, greatly increasing the odds of developing a viable spider silk polymer using silkworms, an animal already domesticated for production. An added benefit for the company is the fact that its particular area of genetic research does not require FDA approval, knocking months or years off the development process.

It now seems at least within the realm of possibility that spider silk will someday be available for lightweight bullet-proof vests, industrial filaments, and a hundred other applications, including perhaps the shirt on your back.

QualityStocks · #19 (**permalink**) 03-09-2009, 02:10 PM

Kraig Biocraft Laboratories, Inc. (KBLB.OB) Continues To Zero In On Commercially Viable Spider Silk

Kraig Biocraft Laboratories, Inc., a Michigan based development stage biotechnology company, is using genetic engineering to develop polymers and high performance fibers for commercial textile and specialty fiber applications. In particular, the company is focused on producing spider silk, one of the strongest fibers produced in nature.

Spider silk is made when spiders spin liquid protein into solid fibers. Spiders can produce a variety of silks, depending upon need, with certain kinds being both strong and flexible. Spider silk has an exceptional ability to absorb and dissipate energy, and, pound for pound, is much stronger than steel. Polymers with the properties of spider silk have long been sought, but spiders, being cannibalistic, cannot be raised in concentrated colonies. For this reason, there is currently no way to produce spider silk in commercial quantities.

But Kraig Biocraft may have finally solved the problem. The company has obtained the exclusive right to use the spider silk gene sequence in this particular field of research. Kraig Biocraft is now in the process of using genetic engineering to allow silkworms, which are much more compatible with commercial production, to produce spider silk.

The company has already successfully inserted spider silk DNA packets into silkworms, and has also confirmed that the insertions are successful and that the silkworms are producing proteins based on the insertions, proving that the research team has indeed altered the silkworm DNA.

Kraig Biocraft also recently announced that the research team, headed by Dr. Malcolm J. Fraser, has performed 5,000 genetic transfers in a single week, an unexpected success. Such volume insertion means a steady stream of different spider silk polymers, any of which could be of commercial significance. According to CEO Kim Thompson, “With this number of gene insertions the odds of our developing a viable polymer are increasing exponentially”.

QualityStocks · #20 (**permalink**) 03-19-2009, 03:37 PM

Kraig Biocraft Laboratories, Inc. (KBLB.OB): What’s So Exciting About Spider Silk?

Spider Silk is one of the strongest fibers found in nature. Along with its incredible strength, the fiber is also extremely elastic and resilient, and has several properties that are unmatched by even the most exotic of man-made fibers. One of the most important properties of spider silk, however, is its extreme resistance to breaking under strain. Relative to this property, spider silk outperforms virtually all known natural and synthetic fibers.

Because spider silk also has the unparalleled capacity to absorb energy and dissipate it in a very controlled manner, this fiber is especially attractive for applications where energy absorption is a key design factor. These applications include bulletproof vests, artificial ligaments, parachute cords, suspension cables and many others.

Pound for pound, spider silk is much stronger than steel. It is known to be at least five times stronger than steel of the same diameter. Spider silk also has some other unique and interesting characteristics. For example, a single strand of spider silk is significantly finer than a human hair as well as substantially lighter. It has been said that spider silk is so thin and light weight that a single strand long enough to circle the entire Earth would weigh less than 2 pounds.

There is little dispute whether or not spider silk has superiority over many manmade and natural fibers for certain applications. However, the issue is how to produce spider silk in commercial quantities at a reasonable cost. With Kraig Biocraft’s leading team of scientific experts and breakthroughs already taking place in the lab, the world is closer than ever to experiencing the many benefits offered by this exciting technology.